I use the desktop version all the time. The only problem with the desktop version it does not support the new authentication method for Amazon S3 and as a result of this it cant connect to S3 buckets in the Frankfurt data center. But the iOS version connects without any issues. Please fix the desktop version as well, just because of this limitation I am searching for alternative on my MacBook Pro.
cannotdecideonanickname about Transmit, v1.3.1